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No tacrolimustreated animals showed any symptoms of rejection while a mild perivascular infiltration was noticed in 1 of the syngeneic management animal. On POD 5, biopsies from allogeneic transplants exhibited Quality I rejection in 3 animals, as effectively as a moderate to serious perivascular swelling with or with out delicate epidermal and/or adnexal epidermal dyskeratosis or apoptosis (Grade